| |
ARDB |
Adrenergic Receptor Targeted
Drug Detail Information |
| Drug Name: |
Acebutolol |
| Full Name: |
Acebutolol hydrochloride |
| Alternative Name: |
Rhotral / Sectral |
| Chinese Name: |
´×¶¡Âå¶û / ´×¶¡õ£ÐÄ°² |
|
|
| Classification: |
Beta-adrenergic antagonist |
| Targeted Receptor: |
Beta-1 |
| Action Type: |
Selective Antagonist |
| Action Detail: |
Predominantly beta-1 blocking activity but will inhibit beta-2 receptors at higher doses. Some intrinsic sympathomimetic activity. |
| |
|
| Indications: |
Hypertension ;
|
| Indication Detail: |
Hypertension (either alone or with other antihypertensive agents such as thiazide diuretics). Premature ventricular contractions. |
| Contraindications: |
Severe, persistent bradycardia. |
| Special Concerns: |
Dosage not established in children. |
|
Side Effects: |
|
| |
|
| Dosage Form: |
Capsule: 200 mg, 400 mg.
|
| Kinectics: |
t1/2: 3-4 hr. Low lipid solubility. Duration: 24-30 hr. Metabolized in liver and excreted in urine and bile. Fifteen to 20% excreted unchanged.< |
| Overdosage Management: |
|
| |
|
|
|
