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ARDB is an integrated resource
about adrenergic receptors (AR), archetypical members of G protein-coupled
receptor (GPCR) superfamily, which play an important role in sympathetic nervous
regulation and are related to many clinical disorders,especially cardiovascular
diseases.
Sequence, structure, mutation and functional data of the components in the
adrenergic singal pathways, such as receptors of different sub-types, ligands,
G proteins and protein kinases, are collected and organized systematically. In
addition, AR-related diseases and clinical AR-targeted drug information are integrated
into this resource as important functional components.
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